Basic calcium phosphate crystals stimulate the endocytotic activity of cells--inhibition by anti-calcification agents.

@article{Sun2003BasicCP,
  title={Basic calcium phosphate crystals stimulate the endocytotic activity of cells--inhibition by anti-calcification agents.},
  author={Yubo Sun and Xiao-rong Zeng and Leonor Wenger and Herman S. Cheung},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={312 4},
  pages={1053-9}
}
Pathological calcifications are associated with many medical conditions including diabetes, breast cancer, and crystals-associated osteoarthritis. The deposition of calcium-containing crystals on cells induces detrimental cellular effects and speeds up the progression of associated diseases. We carried out the present study to test the hypotheses that calcium-containing crystals may stimulate the influx of other molecules existing in the extracellular fluid disturbing normal molecular signaling… CONTINUE READING

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