Basic Fibroblast Growth Factor Gene Expression

@article{Florkiewicz1991BasicFG,
  title={Basic Fibroblast Growth Factor Gene Expression},
  author={Robert Z. Florkiewicz and F Shibata and Teresa J. Barankiewicz and Andre Baird and A. M. Gonz{\'a}lez and Elin Florkiewicz and Najmul Shah},
  journal={Annals of the New York Academy of Sciences},
  year={1991},
  volume={638}
}
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34 Citations
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34 Citations

HOXB7 constitutively activates basic fibroblast growth factor in melanomas

TLDR
A key role for constitutive HOXB7 expression in melanoma cell proliferation via basic fibroblast growth factor (bFGF) mRNA is indicated and the results raise the possibility that growth factor genes are critical HOX target genes in other developmental and/or neoplastic cell systems.

BTN3A3 inhibits the proliferation, migration and invasion of ovarian cancer cells by regulating ERK1/2 phosphorylation

TLDR
BTN3A3 interacts with FGF2, which inhibits F GF2/ERK1/2 axis and ultimately inhibits the proliferation, migration and invasion of ovarian cancer cells.

Review of the Studies on the Anti-Tumoral Effect of Prunella vulgaris

  • W. Mak
  • Biology
    Journal of Biosciences and Medicines
  • 2021
TLDR
The aim of this article was to summarize on what molecular mechanisms, which these previous research found responsible for the anti-tumoral effect of PV.

Functional Roles of FGF Signaling in Early Development of Vertebrate Embryos

TLDR
This review discussed the functional roles of FGFs and their interacting partners as part of the gene regulatory network for germ layer specification, dorsal–ventral (DV), and anterior-posterior (AP) patterning, and briefly reviewed the regulatory molecules and pharmacological agents discovered that may allow modulation of F GF signaling in research.

The synthetic progesterone Norgestrel is neuroprotective in stressed photoreceptor‐like cells and retinal explants, mediating its effects via basic fibroblast growth factor, protein kinase A and glycogen synthase kinase 3β signalling

TLDR
The results indicate that the protective efficacy of Norgestrel is, at least in part, due to the bFGF‐mediated activation of the PKA pathway, with subsequent inactivation of GSK3β.

Altered molecular pattern of mucosal healing in Crohn's disease fibrotic stenosis.

TLDR
Fibrotic stenosis of CD may be the final result of an irreversible transformation of different cells into fibrogenic phenotype no longer inhibited by post-transcriptional regulation.

Why are breast cancer stem cells resistant to radiation

TLDR
The results suggest that low DNA repair capacity is responsible for the high radiosensitivity of these CSC-like cells.

FGF2 (fibroblast growth factor 2 (basic))

Review on FGF2 (fibroblast growth factor 2 (basic)), with data on DNA, on the protein encoded, and where the gene is implicated.

Gastric mucosal injury activates bFGF gene expression and triggers preferential translation of high molecular weight bFGF isoforms through CUG-initiated, non-canonical codons.

Modification of fibrin to improve applications in regenerative medicine

Die Methode von Tissue Engineering oder der Gewebezuchtung drangt uns Matrizen oder Stutzgeruste , die Gewebearten imitieren in vitro zu entwickeln. Tissue Engineering setzt die Prasenz von sich…

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