Basic Concepts and Clinical Findings in the Treatment of Seizure Disorders with EEG Operant Conditioning

  title={Basic Concepts and Clinical Findings in the Treatment of Seizure Disorders with EEG Operant Conditioning},
  author={Maurice B. Sterman},
  journal={Clinical EEG and Neuroscience},
  pages={45 - 55}
  • M. Sterman
  • Published 1 January 2000
  • Psychology, Medicine
  • Clinical EEG and Neuroscience
Two issues concerning sensorimotor EEG operant conditioning, or biofeedback, as a therapeutic modality for the treatment of seizure disorders are the focus of this review. The first relates to the question of whether relevant physiological changes are associated with this procedure. This question is addressed through review of an extensive neurophysiological literature that is likely unfamiliar to many clinicians but that documents both immediate and sustained functional changes that are… 

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EEG feedback training of epileptic patients: clinical and electroencephalographic analysis.
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  • 1988
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