Basement membrane invasion of glioma cells mediated by integrin receptors.

@article{Paulus1994BasementMI,
  title={Basement membrane invasion of glioma cells mediated by integrin receptors.},
  author={W. Paulus and Joerg Christian Tonn},
  journal={Journal of neurosurgery},
  year={1994},
  volume={80 3},
  pages={
          515-9
        }
}
Basement membrane invasion precedes meningeal dissemination and systemic metastasis of glioma cells. In order to investigate the invasive ability of glioblastomas and the functional role of extracellular matrix receptors, the authors performed in vitro invasion assays where the number of cells was determined from freshly resected tumors (primary cultures and fifth passages) and from cell lines (U-138 MG, U-373 MG, and GaMg) that had migrated through a filter coated with a reconstituted basement… CONTINUE READING
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