Basement Membrane Matrix (BME) has Multiple Uses with Stem Cells

  title={Basement Membrane Matrix (BME) has Multiple Uses with Stem Cells},
  author={Irina Arnaoutova and Jay George and Hynda K. Kleinman and Gabriel Benton},
  journal={Stem Cell Reviews and Reports},
The utilization of basement membrane matrix has helped to overcome many of the obstacles associated with stem cell research. Initially, there were several problems with investigating stem cells, including difficult extraction from tissues, the need for feeder layers, poor survival, minimal proliferation, limited differentiation in vitro, and inadequate survival when injected or transplanted in vivo. Given that the basement membrane is the first extracellular matrix that is produced by the… CONTINUE READING
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