Baseline neutrophil-to-lymphocyte ratio is associated with outcome of ipilimumab-treated metastatic melanoma patients

@inproceedings{Ferrucci2015BaselineNR,
  title={Baseline neutrophil-to-lymphocyte ratio is associated with outcome of ipilimumab-treated metastatic melanoma patients},
  author={Pier Francesco Ferrucci and Sara Gandini and Angelo Battaglia and Sergio Alfieri and Anna Maria Di Giacomo and Diana Giannarelli and Gian Carlo Antonini Cappellini and Federica De Galitiis and Paolo Marchetti and Giovanna Amato and Andrea Lazzeri and Laura Pala and Emilia Cocorocchio and Chiara Martinoli},
  booktitle={British Journal of Cancer},
  year={2015}
}
Background:Ipilimumab improves the survival of metastatic melanoma patients. Despite documented, durable objective responses, a significant number of patients fails to benefit from treatment. The aim of this study was to identify an upfront marker for treatment benefit.Methods:A total of 187 metastatic melanoma patients treated in three Italian Institutions with 3 mg kg−1 ipilimumab, and 27 patients treated with 10 mg kg−1 ipilimumab, were evaluated. Neutrophil-to-lymphocyte ratio (NLR) was… CONTINUE READING
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