Base-stabilized nitrilium ions as convenient imine synthons.

Abstract

A simple and efficient methodology is presented for the synthesis of a wide range of substituted imines. It is based on stabilizing readily available, but thermally labile, N-alkylnitrilium triflates with pyridine or DMAP to moderately air-stable adducts. These base-stabilized imine synthons react conveniently with phosphorus- and nitrogen-based… (More)
DOI: 10.1021/acs.orglett.5b00339

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