Base pair substitution and frameshift mutagenesis induced by apurinic sites and two fluorene derivatives in a recA 441 lexA (Def) strain

Abstract

One of the consequences of the induction of the Escherichia coli SOS system is the increased ability of the cells to perform mutagenesis. Induction of the SOS system is the result of derepression of a set of genes through a regulatory mechanism controlled by LexA and RecA. In response to an inducing signal, RecA is activated in a form that facilitates the… (More)
DOI: 10.1007/BF00330522

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