Base-pair probability profiles of RNA secondary structures

  title={Base-pair probability profiles of RNA secondary structures},
  author={M. Schmitz and G. Steger},
  journal={Computer applications in the biosciences : CABIOS},
  volume={8 4},
Dynamic programming algorithms are able to predict optimal and suboptimal secondary structures of RNA. These suboptimal or alternative secondary structures are important for the biological function of RNA. The distribution of secondary structures present in solution is governed by the thermodynamic equilibrium between the different structures. An algorithm is presented which approximates the total partition function by a Boltzmann-weighted summation of optimal and suboptimal secondary… CONTINUE READING