Base-line and postthermal injury plasma histamine in rats.

  title={Base-line and postthermal injury plasma histamine in rats.},
  author={Roger Yurt and Basil A. Pruitt},
  journal={Journal of applied physiology},
  volume={60 5},
Although plasma histamine concentration has been reported to increase after thermal injury in the rat to as much as 100-fold over normal human plasma levels, the pathophysiological significance and relevance to human disease is questionable. Lack of confidence in the rat as a model of histamine-mediated disease is based on reports that normal rat base-line plasma histamine concentration exceeds that of human plasma by 20- to 70-fold. The present study confirms that high concentrations of… CONTINUE READING

From This Paper

Topics from this paper.
13 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…