Base Metal Catalysis in Directed C( sp 3 )−H Functionalisation

@article{StJohnCampbell2019BaseMC,
  title={Base Metal Catalysis in Directed C(
 sp
 3
 )−H Functionalisation},
  author={Sahra St John‐Campbell and James A. Bull},
  journal={Advanced Synthesis \& Catalysis},
  year={2019}
}
14 Citations
Switchable, Reagent-Controlled C(sp3)-H Selective Iodination and Acetoxylation of 8-Methylquinolines.
TLDR
An efficient Pd-catalyzed C(sp3)-H selective iodination of 8-methylquinolines is reported herein for the first time and offers a facile access to various C8-substituted quinolines.
Copper Mediated C(sp2)–H Sulfonylation of Aldehydes using a Catalytic Transient Imine Directing Group
The copper mediated β–C(sp2)–H sulfonylation of benzaldehydes with sulfinate salts is accomplished using β-alanine as a catalytic transient directing group. A broad range of sulfonylated
Remote C(sp3)–H functionalization via catalytic cyclometallation: beyond five-membered ring metallacycle intermediates
Despite impressive recent momentum gained in C(sp3)–H activation, achieving high regioselectivity in molecules containing different C–H bonds with similar high energy without abusing tailored
Mn- and Co-Catalyzed Aminocyclizations of Unsaturated Hydrazones Providing a Broad Range of Functionalized Pyrazolines
TLDR
Cobalt catalysis for the first time paves the way for the selective formation of pyrazoline aldehydes and various functional groups including hydroperoxide, thiol derivatives, iodide, and bicyclopentane may be introduced via manganese-catalyzed ring-forming aminofunctionalization.
Mechanism of 8-Aminoquinoline-Directed Ni-Catalyzed C(sp3)–H Functionalization: Paramagnetic Ni(II) Species and the Deleterious Effect of Carbonate as a Base
Studies into the mechanism of 8-aminoquinoline-directed nickel-catalyzed C(sp3)–H arylation with iodoarenes are described, in an attempt to determine the catalyst resting state and optimize catalytic
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