Basal metabolic rate of aged mice is affected by random genetic drift but not by selective breeding for high early-age locomotor activity or chronic wheel access.

@article{Kane2008BasalMR,
  title={Basal metabolic rate of aged mice is affected by random genetic drift but not by selective breeding for high early-age locomotor activity or chronic wheel access.},
  author={Stephanie L Kane and Theodore Garland and Patrick A. Carter},
  journal={Physiological and biochemical zoology : PBZ},
  year={2008},
  volume={81 3},
  pages={288-300}
}
The study of correlated evolution can lead to new insights about the inheritance patterns of complex traits. In order to better understand the evolution of metabolic rate, we tested whether voluntary activity levels and basal metabolic rate are genetically correlated in 90-wk-old mice (Mus domesticus) from replicated lines of the sixteenth generation of an artificial selection experiment for high early-age wheel-running activity. We measured basal rates of oxygen consumption and carbon dioxide… CONTINUE READING

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