Basal-like breast cancer: update on clinicopathologic, immunohistochemical, and molecular features.

  title={Basal-like breast cancer: update on clinicopathologic, immunohistochemical, and molecular features.},
  author={Jennifer M Leidy and Ashraf Khan and Dina Kandil},
  journal={Archives of pathology & laboratory medicine},
  volume={138 1},
CONTEXT Basal-like breast carcinoma (BLBC) is a distinct molecular subtype of breast carcinoma identified through gene expression profiling studies. OBJECTIVE To provide the clinical background, the histologic profile, and the immunohistochemical profile of these tumors and discuss the current knowledge of their molecular signature and their implications on targeted molecular therapy. DATA SOURCES Data were obtained from review of the pertinent peer-reviewed literature. CONCLUSIONS Basal… CONTINUE READING


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