Basal lamina structural alterations in human asymmetric aneurismatic aorta.

@article{Cotrufo2005BasalLS,
  title={Basal lamina structural alterations in human asymmetric aneurismatic aorta.},
  author={Maurizio Cotrufo and Luca de Santo and Alessandro Della Corte and Franca Di Meglio and Germano Guerra and Cesare Quarto and Serena Vitale and Clotilde Castaldo and Stefania Montagnani},
  journal={European journal of histochemistry : EJH},
  year={2005},
  volume={49 4},
  pages={363-70}
}
Basal lamina (BL) is a crucial mechanical and functional component of blood vessels, constituting a sensor of extracellular microenvironment for endothelial cells and pericytes. Recently, an abnormality in the process of matrix microfibrillar component remodeling has been advocated as a mechanism involved in the development of aortic dilation. We focused our attention on BL composition and organization and studied some of the main components of the Extracellular Matrix such as Tenascin… CONTINUE READING

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