Basal insulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE 901) and NPH insulin.

@article{Rosenstock2001BasalIT,
  title={Basal insulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE 901) and NPH insulin.},
  author={Julio Rosenstock and Sherwyn L Schwartz and Charles M. A. Clark and Glen D Park and David W. Donley and M B Edwards},
  journal={Diabetes care},
  year={2001},
  volume={24 4},
  pages={631-6}
}
OBJECTIVE To determine the safety and efficacy of the long-acting analog insulin glargine compared with NPH insulin in patients with type 2 diabetes who were previously treated with insulin alone. RESEARCH DESIGN AND METHODS A total of 518 subjects with type 2 diabetes who were receiving NPH insulin with or without regular insulin for postprandial control were randomized to receive insulin glargine (HOE 901) once daily (n = 259) or NPH insulin once or twice daily in = 259) for 28 weeks in an… CONTINUE READING
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