Basal forebrain and memory : Neurotoxic lesions impair serial reversals of a spatial discrimination

Abstract

The role of the basal forebrain (BF) in spatial memory was evaluated by testing rats with BF lesions in the acquisition and reversal of a two-choice spatial discrimination. BF lesions were made by injecting ibotenic acid into the medial septal area and nucleus basalis magnocellularis. Behavioral testing was conducted in a T-maze. Rats were given a spatial… (More)

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