Basal dendrites of granule cells are normal features of the fetal and adult dentate gyrus of both monkey and human hippocampal formations

  title={Basal dendrites of granule cells are normal features of the fetal and adult dentate gyrus of both monkey and human hippocampal formations},
  author={L{\'a}szl{\'o} Seress and Ladislav Mrzljak},
  journal={Brain Research},

Atypical features of rat dentate granule cells: recurrent basal dendrites and apical axons

The morphological findings in the present study suggest that rat granule cells are more heterogeneous than previously indicated, and their frequency was not increased in epileptic rats.

Quantitative and morphological analysis of dentate granule cells with recurrent basal dendrites from normal and epileptic rats

Results showed that RBDs of granule cells from epileptic rats are postsynaptic to axon terminals, including mossy fibers, and thus are involved in a similar synaptic circuitry as apical dendrites of granules cells from these animals.

Maturation of granule cell dendrites after mossy fiber arrival in hippocampal field CA3

It is shown that dendritic outgrowth occurs before, or concurrent with, axon arrival in the CA3 target region, and that adult‐like granule neurons are present by the end of the first week.

Granule cells of the dentate gyrus with basal and recurrent dendrites in schizophrenic patients and controls. A comparative Golgi study

A significantly higher incidence of granule cells with basal dendrites in brains of schizophrenic patients is found, which is interpreted as a plastic reaction to prenatal developmental malformations of the impinging rostral entorhinal region.

Morphology of dentate granule cells in the human epileptogenic hippocampus

Factor analysis performed on the morphometric features of each group of neurons reveals that in the MaTLE neurons the most distinctive feature is the total dendritic length and the overall distribution of spines on them, whereas in MTLE a lengthening and elaboration of the dendrites in the IML is most distinctive.

Increased frequency of dentate granule cells with basal dendrites in the hippocampal formation of schizophrenics

Morphology and electrophysiology of dentate granule cells in the rhesus monkey: Comparison with the rat

There is significant conservation of both form and function in dentate granule cells in these two species, despite the enormous phylogenetic separation, which suggests that granule cell properties may be extremely stable across diverse mammalian species.

fmtures of primate granule cell budlee show Import&H differences from those of rats: axogomatlc synapses, somatic spines and Infolded nuclei

The reduced number of axosomatic synapses in monkeys suggests that local inhibitory connections of primate granule cells are less than that of rodents, and the relative numbers of symmetric and asym synapses are higher than previously reported.



Differentiation of granule cell dendrites in the dentate gyrus of the rhesus monkey: A quantitative golgi study

Quanti‐tative analysis shows that, in this primate, hippocampal granule cells dif‐ferentiate mainly in the second half of gestation with all measured param‐eters attaining mature values by the time of birth, however, the analysis also reveals a transient phase of exuberant postnatal development which involves excessive dendritic branching, regional changes in dendedritic length, overproduction of dendrite spines, and redistribution of spines within the molecular layer.

The commissural connections of the monkey hippocampal formation

The commissural connections of the hippocampal formation have been analyzed in the monkey using both anterograde and retrograde labeling techniques and a number of striking differences are observed.

Structure of the granular layer of the rat dentate gyrus. A light microscopic and Golgi study.

The possible role of basket cells in the regulation of the dentate gyrus granular layer was considered and several axon collaterals could be seen on the granule cell axons.

Interhemispheric pathways of the hippocampal formation, presubiculum, and entorhinal and posterior parahippocampal cortices in the rhesus monkey: The structure and organization of the hippocampal commissures

The ventral hippocampal commissure and dorsal hippocampal Commissure of the rhesus monkey appear to be homologous to similarly designated structures in other mammals, and their possible preservation must be considered when interpreting the effect of callosal transection on seizures and the results of “split‐brain” studies.

A quantitative anatomical study of the granule cell dendritic fields of the rat dentate gyrus using a novel probabilistic method

The granule cell dendritic fields of the adult rat dentate gyrus were analyzed quantitatively using a probabilistic method developed to correct dendritic length and segment number for dendrites cut