Basal cortisol in serum and saliva as a screening parameter for secondary adrenal insufficiency

@inproceedings{Deutschbein2006BasalCI,
  title={Basal cortisol in serum and saliva as a screening parameter for secondary adrenal insufficiency},
  author={Timo Deutschbein and Nicole Unger and Klaus Mann and Stephan Petersenn},
  year={2006}
}
Objectives: The insulin tolerance test (ITT) is considered the gold standard to evaluate corticotropic function in patients with suspected pituitary disease, but is limited by several contraindications. As an alternative, we evaluated the diagnostic value of basal cortisol in serum and saliva. Methods: 188 volunteers (V) (112 M, 76 F; age 37.4±13.5; BMI 26.5±5.1) and 61 patients with suspected pituitary disease (P) (32 M, 29 F, age 45.6±2.0; BMI 28.4±0.6) were enrolled into this study. Basal… CONTINUE READING