Basal cell carcinoma xenografts in nude mice: studies on epithelial differentiation and stromal relationships.

Abstract

Thirty-three basal cell carcinomas (BCC) were transplanted into athymic mice, and foci of tumour were identified in 17 grafts recovered after intervals of 2-5 months. Fifteen of these xenografts contained apparently normal differentiated epithelia, considered to derive from elements within the original tumours. The level of differentiation was very close in… (More)

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