Basal caspase-3 activity promotes migration, invasion, and vasculogenic mimicry formation of melanoma cells.

@article{Liu2013BasalCA,
  title={Basal caspase-3 activity promotes migration, invasion, and vasculogenic mimicry formation of melanoma cells.},
  author={Yan-rong Liu and Baocun Sun and Xiulan Zhao and Qiang Gu and Zhi-yong Liu and Xue-yi Dong and Na Che and Jing Mo},
  journal={Melanoma research},
  year={2013},
  volume={23 4},
  pages={243-53}
}
Melanoma is the least common but most serious form of skin cancer. The leading cause of death in melanoma patients is widespread metastasis caused by increased cell motility and a rich blood supply for tumor cells. A unique form of microcirculation called vasculogenic mimicry, which efficiently supplies blood to tumor cells, has been reported recently. Apoptosis-related protein performs a nonapoptotic function to promote migration and invasion of tumor cells. This study focuses on the… CONTINUE READING
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