Basal body multipotency and axonemal remodelling are two pathways to a 9+0 flagellum

@inproceedings{Wheeler2015BasalBM,
  title={Basal body multipotency and axonemal remodelling are two pathways to a 9+0 flagellum},
  author={Richard John Wheeler and Eva Gluenz and Keith Gull},
  booktitle={Nature communications},
  year={2015}
}
Eukaryotic cilia/flagella exhibit two characteristic ultrastructures reflecting two main functions; a 9+2 axoneme for motility and a 9+0 axoneme for sensation and signalling. Whether, and if so how, they interconvert is unclear. Here we analyse flagellum length, structure and molecular composition changes in the unicellular eukaryotic parasite Leishmania during the transformation of a life cycle stage with a 9+2 axoneme (the promastigote) to one with a 9+0 axoneme (the amastigote). We show 9+0… CONTINUE READING
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