Basal and histamine-induced gastric acid secretion in alloxan diabetic rats.

@article{Ozcelikay1993BasalAH,
  title={Basal and histamine-induced gastric acid secretion in alloxan diabetic rats.},
  author={Arif Tanju Ozcelikay and Vecdi Melih Altan and N Yildizoğlu-ari and O Altinkurt and Feyyaz Onur and Yusuf Ozt{\"u}rk},
  journal={General pharmacology},
  year={1993},
  volume={24 1},
  pages={121-6}
}
1. Effects of alloxan-induced diabetes on the rat gastric acid secretion were investigated using a number of biostatistical models described earlier. 2. Histamine-induced gastric acid secretion was found to be decreased in alloxan-diabetic rats when compared with their age-matched controls. 3. Basal acid secretion was also decreased depending on experimentally-induced diabetes. 4. The above results strongly suggest that alloxan-induced diabetes depresses vagal activity and H2-receptor activity… CONTINUE READING