Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-alpha ligands in Zucker rats.

@article{Izzo2010BasalAF,
  title={Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-alpha ligands in Zucker rats.},
  author={Angelo A Izzo and Fabiana Piscitelli and Raffaele Capasso and Pietro Marini and Luigia Cristino and Stefania Petrosino and Vincenzo Di Marzo},
  journal={Obesity},
  year={2010},
  volume={18 1},
  pages={55-62}
}
N-oleoylethanolamine (OEA) and N-palmitoylethanolamine (PEA) are endogenous lipids that activate peroxisome proliferator-activated receptor-alpha with high and intermediate potency, and exert anorectic and anti-inflammatory actions in rats, respectively. We investigated OEA and PEA tissue level regulation by the nutritional status in lean and obese rats. OEA and PEA levels in the brainstem, duodenum, liver, pancreas, and visceral (VAT) or subcutaneous (SAT) adipose tissues of 7-week-old wild… CONTINUE READING