Basal NO locally modulates human iliac artery function in vivo.

  title={Basal NO locally modulates human iliac artery function in vivo.},
  author={Matthias O Schmitt and Albert P. Avolio and Ahmad Qasem and Carmel M McEniery and Mark Butlin and Ian B. Wilkinson and John R. Cockcroft},
  volume={46 1},
We demonstrated previously that endogenous NO influences large-artery distensibility in the ovine hindlimb. However, the role of basal NO in larger human conduit arteries is controversial. The aim of this study was to investigate whether basal production of NO, acting locally, influences iliac artery distensibility in humans. Distensibility was assessed by intra-arterial measurement of the pulse wave velocity. Eighteen subjects, free of significant coronary or iliac artery disease, were studied… CONTINUE READING