Bartter syndrome: unraveling the pathophysiologic enigma.

  title={Bartter syndrome: unraveling the pathophysiologic enigma.},
  author={L. M. Guay-Woodford},
  journal={The American journal of medicine},
  volume={105 2},
Familial hypokalemic, hypochloremic metabolic alkalosis, or Bartter syndrome, is not a single disorder but rather a set of closely related disorders. These Bartter-like syndromes share many of the same physiologic derangements, but differ with regard to the age of onset, the presenting symptoms, the magnitude of urinary potassium (K) and prostaglandin excretion, and the extent of urinary calcium excretion. At least three clinical phenotypes have been distinguished: (1) classic Bartter syndrome… CONTINUE READING