Bartonella henselae inhibits apoptosis in Mono Mac 6 cells.

  title={Bartonella henselae inhibits apoptosis in Mono Mac 6 cells.},
  author={Volkhard A. J. Kempf and Annette Schairer and Diana Neumann and Guntram Grassl and Kirsten Lauber and Maria Lebiedziejewski and Martin Schaller and Pierre Kyme and Sebastian Wesselborg and I. Autenrieth},
  journal={Cellular microbiology},
  volume={7 1},
Bartonella henselae causes the vasculoproliferative disorders bacillary angiomatosis and peliosis probably resulting from the release of vasculoendothelial growth factor (VEGF) from infected epithelial or monocytic host cells. Here we demonstrate that B. henselae in addition to VEGF induction was also capable of inhibiting the endogenous sucide programme of monocytic host cells. Our results show that B. henselae inhibits pyrrolidine dithiocarbamate (PDTC)-induced apoptosis in Mono Mac 6 cells… CONTINUE READING


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