Bartonella henselae infection in a man with hypergammaglobulinaemia, splenomegaly and polyclonal plasmacytosis.

@article{Balakrishnan2013BartonellaHI,
  title={Bartonella henselae infection in a man with hypergammaglobulinaemia, splenomegaly and polyclonal plasmacytosis.},
  author={Nandhakumar Balakrishnan and Jaspaul S Jawanda and Melissa B. Miller and Edward B. Breitschwerdt},
  journal={Journal of medical microbiology},
  year={2013},
  volume={62 Pt 2},
  pages={
          338-41
        }
}
Bartonella henselae is an infrequently reported cause of polyclonal plasmacytosis and hypergammaglobulinaemia. We herein document B. henselae infection in a 66-year-old patient who presented with hypergammaglobulinaemia, splenomegaly with polyclonal plasmacytosis, stroke, and suspected prosthetic aortic arch infection. Clinicians should remain cognizant of the heterogeneous clinical presentations associated with bartonellosis. 
View on PubMed
doi.org
11 Citations
Background Citations
5

Figures from this paper

11 Citations

Citation Type

Citation Type

Prostatitis, Steatitis, and Diarrhea in a Dog following Presumptive Flea-Borne Transmission of Bartonella henselae
TLDR
A dog developed an unusual clinical presentation for canine bartonellosis following an acute flea infestation, and comprehensive medical, microbiological, and surgical interventions were required for diagnosis and to achieve a full recovery.
Did Bartonella henselae contribute to the deaths of two veterinarians?
TLDR
Bartonella henselae may or may not have been responsible for the deaths of two veterinarians, and recent evidence indicates that this genus is of much greater medical importance than is currently appreciated by the majority of the biomedical community.
Famotidine-induced reactive plasmacytosis and generalized lymphadenopathy : a case report and review of the literature
TLDR
The present case represents the first report of marked famotidine-associated plasmacytosis, and the patient had high serum IgE levels that decreased after discontinuation of the medications.
Bartonella Quintana prosthetic aortitis successfully treated with doxycycline
TLDR
A case of ascending aortic prosthetic graft infection due to B. quintana is described in a patient with past unrecognised necrotising aortitis, which was successfully treated with doxycycline monotherapy.
Splenic vasculitis, thrombosis, and infarction in a febrile dog infected with Bartonella henselae.
TLDR
A potential role for this bacterium as a cause of vasculitis and thromboembolism, which have not been previously reported in association with B. henselae infection in dogs, is established.
Bartonellosis, One Health and all creatures great and small
TLDR
This review serves as an update on comparative medical aspects of this disease, including the epidemiology, pathogenesis, clinical diagnosis, treatment and challenges, and concludes that directed Bartonella research could substantially reduce a spectrum of chronic and debilitating animal and human diseases, and thereby reduce suffering throughout the world.
Bartonella spp. Bloodstream Infection in a Canadian Family.
TLDR
There is a substantial need for clinical research to clarify the extent to which Bartonella spp.
Co-infection with Anaplasma platys, Bartonella henselae, Bartonella koehlerae and ‘Candidatus Mycoplasma haemominutum’ in a cat diagnosed with splenic plasmacytosis and multiple myeloma
TLDR
Co-infection with multiple vector-borne pathogens should be a diagnostic consideration in cats with chronic hypergammaglobulinemia, monoclonal gammopathy and splenic plasmacytosis.
Pyogranulomatous Pancarditis with Intramyocardial Bartonella henselae San Antonio 2 (BhSA2) in a Dog
TLDR
A 6-year-old, female, spayed American Pitbull terrier was presented for progressive lethargy, weakness, and anorexia of 3-weeks duration, and found to have metabolic acidosis and Lyme quantitative C6 ELISA was negative.
One Health and all creatures great and small
TLDR
Directed Bartonella research could substantially reduce a spectrum of chronic and debilitating animal and human diseases, and thereby reduce suffering throughout the world.
...
...

References

SHOWING 1-10 OF 13 REFERENCES
Monoclonal and biclonal gammopathy in two patients infected with Bartonella henselae
TLDR
Cat-scratch disease should be added to the list of possible underlying disorders in individuals presenting with monoclonal and biclonal gammopathy, due to infection with Bartonella henselae.
Bartonella henselae infection mimicking a splenic lymphoma.
We report a Bartonella henselae infection in a 40-y-old patient who presented with fever, weight loss, night sweats, elevated lactate dehydrogenase and multinodular splenomegaly with multiple…
Bartonella Species in Blood of Immunocompetent Persons with Animal and Arthropod Contact
Using PCR in conjunction with pre-enrichment culture, we detected Bartonella henselae and B. vinsonii subspecies berkhoffii in the blood of 14 immunocompetent persons who had frequent animal contact…
Endocarditis in a dog due to infection with a novel Bartonella subspecies
TLDR
P phenotypic and genotypic characterization of the isolate indicated that this organism, which can induce endocarditis in dogs, is a novel Bartonella subspecies containing an insertion sequence unique among currently recognized Bart onella species.
Comprehensive diagnostic strategy for blood culture-negative endocarditis: a prospective study of 819 new cases.
  • P. Fournier, F. Thuny, D. Raoult
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2010
TLDR
A prospective, multimodal strategy incorporating serological, molecular, and histopathological assays to investigate specimens from 819 patients suspected of having blood culture-negative endocarditis highlights the major role of zoonotic agents and the underestimated role of noninfective diseases in BCNE.
Hallucinations, Sensory Neuropathy, and Peripheral Visual Deficits in a Young Woman Infected with Bartonella koehlerae
ABSTRACT A young woman experiencing depression, anxiety, mood swings, severe headaches, muscle spasms, interphalangeal joint stiffness, decreased peripheral vision, diminished tactile sensation, and…
Novel Chemically Modified Liquid Medium That Will Support the Growth of Seven Bartonella Species
TLDR
A novel, chemically modified, insect-based liquid culture medium is described that supports the growth of at least seven Bartonella species and may provide an advantage over conventional direct blood agar plating for the diagnostic confirmation of bartonellosis.
Cross-contamination in the Molecular Detection of Bartonella from Paraffin-embedded Tissues
TLDR
Unless stringent procedures are established and followed to avoid cross-contamination, the molecular detection of Bartonella spp.
Manual of clinical microbiology
TLDR
A collaborative team of editors and authors from around the world revised the Manual to include the latest applications of genomics and proteomics, producing an authoritative work of two volumes filled with current findings regarding infectious agents, leading-edge diagnostic methods, laboratory practices, and safety guidelines.
Evaluation of the MicroSeq 500 16S rDNA-based gene sequencing for the diagnosis of culture-negative bacterial meningitis.
TLDR
The MicroSeq 500 16S ribosomal DNA test may improve the microbiological diagnosis of bacterial meningitis, especially when spinal fluid samples are obtained after the administration of antimicrobial therapy.
...
...