Bartonella henselae infection in a man with hypergammaglobulinaemia, splenomegaly and polyclonal plasmacytosis.

@article{Balakrishnan2013BartonellaHI,
  title={Bartonella henselae infection in a man with hypergammaglobulinaemia, splenomegaly and polyclonal plasmacytosis.},
  author={Nandhakumar Balakrishnan and Jaspaul S Jawanda and Melissa B. Miller and Edward B. Breitschwerdt},
  journal={Journal of medical microbiology},
  year={2013},
  volume={62 Pt 2},
  pages={
          338-41
        }
}
Bartonella henselae is an infrequently reported cause of polyclonal plasmacytosis and hypergammaglobulinaemia. We herein document B. henselae infection in a 66-year-old patient who presented with hypergammaglobulinaemia, splenomegaly with polyclonal plasmacytosis, stroke, and suspected prosthetic aortic arch infection. Clinicians should remain cognizant of the heterogeneous clinical presentations associated with bartonellosis. 
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Bartonella henselae may or may not have been responsible for the deaths of two veterinarians, and recent evidence indicates that this genus is of much greater medical importance than is currently appreciated by the majority of the biomedical community.
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There is a substantial need for clinical research to clarify the extent to which Bartonella spp.
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Co-infection with multiple vector-borne pathogens should be a diagnostic consideration in cats with chronic hypergammaglobulinemia, monoclonal gammopathy and splenic plasmacytosis.
Pyogranulomatous Pancarditis with Intramyocardial Bartonella henselae San Antonio 2 (BhSA2) in a Dog
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A 6-year-old, female, spayed American Pitbull terrier was presented for progressive lethargy, weakness, and anorexia of 3-weeks duration, and found to have metabolic acidosis and Lyme quantitative C6 ELISA was negative.
One Health and all creatures great and small
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Directed Bartonella research could substantially reduce a spectrum of chronic and debilitating animal and human diseases, and thereby reduce suffering throughout the world.

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