Barriers and more: functions of tight junction proteins in the skin

@article{Kirschner2012BarriersAM,
  title={Barriers and more: functions of tight junction proteins in the skin},
  author={N. Kirschner and J. Brandner},
  journal={Annals of the New York Academy of Sciences},
  year={2012},
  volume={1257}
}
Although the existence of tight junction (TJ) structures (or a secondary epidermal barrier) was postulated for a long time, the first description of TJ proteins in the epidermis (occludin, ZO‐1, and ZO‐2) was only fairly recent. Since then, a wealth of new insights concerning TJs and TJ proteins, including their functional role in the skin, have been gathered. Of special interest is that the epidermis as a multilayered epithelium exhibits a very complex localization pattern of TJ proteins… Expand
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