Barrett's oesophagus

  title={Barrett's oesophagus},
  author={N. Shaheen and J. Richter},
  journal={The Lancet},
  • N. Shaheen, J. Richter
  • Published 2009
  • Medicine
  • The Lancet
  • Barrett's oesophagus is a metaplastic change of the lining of the oesophagus, such that the normal squamous epithelium is replaced by specialised or intestinalised columnar epithelium. The disorder seems to be a complication of chronic gastro-oesophageal reflux disease, although asymptomatic individuals might also be affected, and it is a risk factor for the development of oesophageal adenocarcinoma, a cancer with rapidly increasing incidence in developed societies. We review the presentation… CONTINUE READING
    87 Citations

    Paper Mentions

    Interventional Clinical Trial
    The increasing incidence of Esophageal Adenocarcinoma (EAC) in several Western countries can be primarily ascribed to risk factors such as obesity, chronic gastroesophageal reflux… Expand
    ConditionsBarrett's Esophagus, Overweight and Obesity
    Interventional Clinical Trial
    The accurate detection and therapy of adenocarcinoma originating from Barrett's oesophagus is challenging as current endoscopic techniques are unreliable for both the detection of high… Expand
    ConditionsBarrett's Mucosa With High Grade Intraepithelial Neoplasia (HGIEN)
    Endoscopic Detection and Eradication of Dysplastic Barrett's Oesophagus
    • 2
    • Highly Influenced
    • PDF
    Management controversies in Barrett’s oesophagus
    • 5
    Biomarkers of the effect of gastrin on Barrett's oesophagus
    • Highly Influenced
    • PDF
    Barrett ’ s oesophagus screening and surveillance
    Cost-effectiveness of Barrett's oesophagus screening and surveillance.
    • 11
    • PDF
    How Good Is the Neosquamous Epithelium?
    • 12


    Risk factors for Barrett's oesophagus: a life history approach to behavioural assessment in the distant past
    • 20
    Clinical Use of p53 in Barrett's Esophagus
    • 42
    • PDF
    Cdx2 as a Marker of Epithelial Intestinal Differentiation in the Esophagus
    • 235