Barrett's esophagus: clinical characteristics.

  title={Barrett's esophagus: clinical characteristics.},
  author={James C. Reynolds and Poneh Rahimi and David A Hirschl},
  journal={Gastroenterology clinics of North America},
  volume={31 2},
Barrett's metaplasia develops in 6-14% of individuals with gastroesophageal reflux. Barrett's adenocarcinomas are increasing in epidemic proportions for as yet unknown reasons, approximately 0.5-1% of patients with Barrett's will develop adenocarcinoma. Heartburn duration and frequency (but not severity), male gender, and Caucasian race are major risk factors for developing cancer. Obesity and smoking are weak risk factors. Survival is determined by depth of tumor invasion (stage). Once… CONTINUE READING