Barrett's esophagus: cell cycle abnormalities in advancing stages of neoplastic progression.

@article{Reid1993BarrettsEC,
  title={Barrett's esophagus: cell cycle abnormalities in advancing stages of neoplastic progression.},
  author={Brian J. Reid and Carissa A. Sanchez and Patricia L. Blount and Douglas S. Levine},
  journal={Gastroenterology},
  year={1993},
  volume={105 1},
  pages={119-29}
}
BACKGROUND Abnormal proliferation in Barrett's esophagus may predispose to the development of esophageal adenocarcinoma, but previous studies have not determined the specific cell cycle abnormalities that were associated with neoplastic progression. METHODS Ki67/DNA content multiparameter flow cytometry and DNA content flow cytometry were used to investigate G0, G1, and S phase fractions in advancing stages of neoplastic progression in Barrett's esophagus. RESULTS In control biopsy… CONTINUE READING
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