Barrett's esophagus, dysplasia, and adenocarcinoma.

  title={Barrett's esophagus, dysplasia, and adenocarcinoma.},
  author={Rodger C. Haggitt},
  journal={Human pathology},
  volume={25 10},
In Barrett's esophagus the normal stratified squamous epithelium lining the esophagus becomes replaced by metaplastic columnar epithelium containing goblet cells; it develops as a complication of chronic gastroesophageal reflux disease and predisposes the patient to adenocarcinoma. The frequency with which it leads to adenocarcinoma is not established with certainty, but the reported prevalence averages approximately 10% when the diagnosis of Barrett's esophagus is first made. The estimated… CONTINUE READING
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