Barotrauma and microvascular injury in lungs of nonadult rabbits: effect of ventilation pattern.

@article{Peevy1990BarotraumaAM,
  title={Barotrauma and microvascular injury in lungs of nonadult rabbits: effect of ventilation pattern.},
  author={Keith J. Peevy and Lisa A Hernandez and Alicia A Moise and James Courtney Parker},
  journal={Critical care medicine},
  year={1990},
  volume={18 6},
  pages={634-7}
}
To study the pulmonary microvascular injury produced by ventilation barotrauma, the isolated perfused lungs of 4 to 6-wk-old New Zealand white rabbits were ventilated by one of the following methods: peak inspiratory pressure (PIP) 23 cm H2O, gas flow rate 1.1 L/min (group 1); PIP 27 cm H2O, gas flow rate 6.9 L/min (group 2); PIP 50 cm H2O, gas flow rate 1.9 L/min (group 3); or PIP 53 cm H2O, gas flow rate 8.3 L/min (group 4). Microvascular permeability was assessed using the capillary… CONTINUE READING

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