Baroreceptor reflex modulation by angiotensin II at the nucleus tractus solitarii.

@article{CampagnoleSantos1988BaroreceptorRM,
  title={Baroreceptor reflex modulation by angiotensin II at the nucleus tractus solitarii.},
  author={Maria Jos{\'e} Campagnole-Santos and D Iglesias Diz and Carlos Maria Ferrario},
  journal={Hypertension},
  year={1988},
  volume={11 2 Pt 2},
  pages={
          I167-71
        }
}
This study characterized the effect of nucleus tractus solitarii (NTS) microinjection of the angiotensin II (Ang II) antagonist [Sar1, Thr8]Ang II on the baroreceptor control of heart rate in anesthetized rats. Reflex changes in heart rate were elicited by bolus intravenous injections of either phenylephrine or sodium nitroprusside before and after bilateral microinjection of [Sar1, Thr8]Ang II (100 pmol) or vehicle into the NTS. The slope of the relationship between the change in pulse… CONTINUE READING

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