Baroreceptor denervation presenting as part of a vagal mononeuropathy


A 48-year-old woman presented with a history of progressive cough, dysphonia, dysphagia, and postural symptoms. Subsequent neurological investigations were consistent with a bilateral vagal mononeuropathy, and neurosarcoidosis was diagnosed after scalene node biopsy. Autonomic investigations including microneurography, neurohormones, and heart rate variability demonstrated arterial and cardiopulmonary baroreflex failure. In addition, parasympathetic control of heart rate was absent and consistent with a bilateral, nonselective lesion in the proximal vagus.

DOI: 10.1007/BF02279894

10 Figures and Tables

Cite this paper

@article{FRACP2000BaroreceptorDP, title={Baroreceptor denervation presenting as part of a vagal mononeuropathy}, author={D. L. Jardine F.R.A.C.P. and I. C. Melton F.R.A.C.P. and S. I. Bennett N.Z.C.S. and Ian George Crozier and Ivan M Donaldson and Haseeb Ikram}, journal={Clinical Autonomic Research}, year={2000}, volume={10}, pages={69-75} }