Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

  title={Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis},
  author={Peter W. Horby and J. R. Emberson and Marion M. Mafham and M. I. Campbell and Leon Peto and Guilherme Pessoa-Amorim and Enti Spata and Natalie Staplin and Catherine Lowe and David R. Chadwick and C E Brightling and Rachel Stewart and P. Collini and Abdul Ashish and Chloe Green and Benjamin Prudon and T. W. Felton and Anthony Kerry and John Kenneth Baillie and M. H. Buch and Jo Day and S. N. Faust and Thomas F. Jaki and Katie Jeffery and Edmund Juszczak and Matthew Knight and Wei Shen Lim and Adam Montgomery and Andrew Mumford and Kathy Rowan and Ge E. Thwaites and Richard Haynes and Martin J Landray},
Background: We evaluated the use of baricitinib, a Janus kinase (JAK) 1/2 inhibitor, for the treatment of patients admitted to hospital because of COVID-19. Methods: This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple possible treatments in patients hospitalised for COVID-19. Eligible and consenting patients were randomly allocated (1:1) to either usual standard of care alone (usual care group) or usual care plus… 
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