Bariatric surgery improves nonalcoholic fatty liver disease: a contemporary systematic review and meta-analysis.

@article{Fakhry2019BariatricSI,
  title={Bariatric surgery improves nonalcoholic fatty liver disease: a contemporary systematic review and meta-analysis.},
  author={Tannous K. Fakhry and Rahul S. Mhaskar and Theresa A. Schwitalla and Elnara Muradova and John Paul Gonzalvo and Michel M. Murr},
  journal={Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery},
  year={2019},
  volume={15 3},
  pages={
          502-511
        }
}
  • Tannous K. FakhryR. Mhaskar M. Murr
  • Published 1 March 2019
  • Medicine
  • Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

Bariatric Surgery Improves Nonalcoholic Fatty Liver Disease: Systematic Review and Meta-Analysis

It is revealed that bariatric surgery brought out significantly resolution of NAFLD in individuals with obesity, and RYGB and SG have been proved to be of benefit to many hepatic parameters, and the improvement of liver steatosis and fibrosis, particularly in Asian countries.

Bariatric surgery for non-alcoholic fatty liver disease in individuals with obesity (Base-NAFLD): protocol of a prospective multicenter observational follow-up study

This prospective multicentre observational follow-up study will include 142 obese patients with NAFLD scheduled to undergo one of the following surgical procedures: sleeve gastrostomy, Roux-en-Y gastric bypass, and one anastomosis Gastric bypass to provide a necessary and preliminary foundation for the early identification and targeted treatment of patients withNAFLD who can be referred for bariatric surgery, as indicated for management of obesity and metabolic disease.

Management of nonalcoholic fatty liver disease and the role of bariatric surgery: a brief review for surgeons.

Bariatric Surgery Decreases the Progression of Nonalcoholic Fatty Liver Disease to Cirrhosis.

The case made in this issue of Annals of Surgery for bariatric surgery as it relates to nonalcoholic fatty liver disease is reviewed, with a strong case for NAFLD to become an acceptable comorbid condition forbariatric surgery enrollment.

Gastric Bypass Compared with Sleeve Gastrectomy for Nonalcoholic Fatty Liver Disease: a Systematic Review and Meta-analysis

SG and RYGB are equivalently effective for treatingNAFLD/NASH and the NAFLD Activity Score was significantly improved after both procedures, as well as biochemical tests.

The role of bariatric surgery in the management of nonalcoholic steatohepatitis

Resolution of NASH and fibrosis regression can occur after bariatric surgery, and emerging data on this topic is vitally important for lending insight into the pharmacotherapies for NASH for patients who are not otherwise suitable candidates forbariatric surgery.

Improvement of hepatic steatosis and fibrosis in diabetes: Which bariatric procedure is more appropriate?

  • W. Jia
  • Medicine
    Journal of diabetes investigation
  • 2022
The non-alcoholic fatty liver disease (NAFLD) epidemic poses a major public health issue globally, affecting around 25% of the population worldwide, and has a close association with type 2 diabetes,

Long-term effects of one-anastomosis gastric bypass on liver histopathology in NAFLD cases: a prospective study

OAGB resolved NASH from nearly 42% of patients and reduced the histological features of NAFLD 15 months after surgery and bariatric procedures might be adopted as a therapeutic modality in severely obese cases withNAFLD after the failure of lifestyle modifications.

Impact of sleeve gastrectomy and Roux-en-Y gastric bypass on biopsy-proven non-alcoholic fatty liver disease

In patients with biopsy-proven NAFLD/NASH, abnormal LFTs are normalized in most SG and RYGB patients by the end of the first postoperative year and remain normal until the last follow-up, suggesting that both bariatric procedures are similarly effective in improving liver function.

Bariatric Surgery Reduces Cancer Risk in Adults with Nonalcoholic Fatty Liver Disease and Severe Obesity.

Bariatric surgery was associated with significant reductions in the risks of any cancer and obesity-related cancer in NAFLD patients with severe obesity.
...

References

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Effect of bariatric surgery on nonalcoholic fatty liver disease: systematic review and meta-analysis.

Bariatric Surgery and Non-Alcoholic Fatty Liver Disease: a Systematic Review of Liver Biochemistry and Histology

Bariatric surgery is associated with a significant improvement in both histological and biochemical markers ofNAFLD, and future studies must focus on higher levels of evidence to better identify the benefits of bariatric surgery on liver disease in order to enhance future treatment strategies in the management of NAFLD.

Improvement of Nonalcoholic Fatty Liver Disease After Bariatric Surgery in Morbidly Obese Chinese Patients

Bariatric surgery can achieve a dramatic improvement of NAFLD both biochemically and histologically in morbidly obese Chinese patients.

Bariatric surgery for non-alcoholic steatohepatitis in obese patients.

The lack of randomised clinical trials and quasi-randomised clinical studies precludes the benefits and harms of bariatric surgery as a therapeutic approach for patients with NASH.

Effect of Roux-en-y Gastric Bypass on Nonalcoholic Fatty Liver Disease Evaluated Through NAFLD Fibrosis Score: a Prospective Study

Nonalcoholic fatty liver disease is common among subjects who undergo bariatric surgery and its postsurgical improvement has been reported, but RYGB leads to a great resolution rate of liver fibrosis.

Roux-en-Y gastric bypass improves liver histology in patients with non-alcoholic fatty liver disease.

Improvement in all of the histological features of NAFLD after Roux-en-Y gastric bypass surgery-induced weight loss is shown, despite significant histopathology at baseline and substantial weight loss.

Non-alcoholic fatty liver disease resolution following sleeve gastrectomy

Weight loss after LSG effectively resolved non-alcoholic fatty liver disease in more than half of the obese patients in this study and can prove to be a useful tool in tackling the disease in the future.

Resolution of Nonalcoholic Steatohepatits after Gastric Bypass Surgery

Over a mean period of 18 months, histological improvements and resolution of NASH occurs after LRYGBP, and long-term studies are warranted to assess for potential changes in the portal regions or relapse ofNASH that could result with weight regain or malnutrition.

Non-Alcoholic Steatohepatitis: Effect of Roux-en-Y Gastric Bypass Surgery

Weight loss after Roux-en-Y gastric bypass surgery in obese patients with NASH results in significant improvement in glucose, HgbA1c.