Gastrointestinal weight loss surgery for the management of type 2 diabetes: A view from Greece
- MedicineHellenic Journal of Surgery
Evidence is provided that surgical procedures bypassing parts of the small intestine improve glucose homeostasis through mechanisms beyond reduced food intake and body weight, which should facilitate the design of novel anti-diabetic gastrointestinal manipulations, devices and pharmacotherapeutics for obese and non-obese diabetic patients.
Bariatric surgery or medicine for type 2 diabetes?
- MedicineExpert opinion on pharmacotherapy
Larger studies are needed to determine whether one of these procedures is better, or if they are all similarly effective, and this should be weighed against the risk of the operations.
Metabolic surgery for type 2 diabetes: efficacy and risks
- MedicineCurrent opinion in endocrinology, diabetes, and obesity
Understanding the efficacy and physiologic effects of bariatric surgery on metabolism will help guide patient management in the context of a growing epidemic of obesity and T2DM, and may also enable us to develop less invasive but equally effective therapeutic strategies for weight loss and metabolic control.
Glycaemic Control and Reduction of Cardiovascular Risk Following Bariatric Surgery
- Medicine, Biology
This chapter will outline the differential effects of each of the current most common bariatric procedures on CV risk factors.
Assessing the obese diabetic patient for bariatric surgery: which candidate do I choose?
- MedicineDiabetes, metabolic syndrome and obesity : targets and therapy
At present, Roux-en-Y gastric bypass seems the surgical procedure of choice because it has fewer risks than biliopancreatic diversion, and it is associated with higher weight loss and metabolic improvements compared with adjustable gastric banding.
Gastrointestinal Surgery: Cardiovascular Risk Reduction and Improved Long-Term Survival in Patients with Obesity and Diabetes
- MedicineCurrent Atherosclerosis Reports
The opportunity for bariatric (and/or metabolic) surgery to provide a preventive strategy for cardiovascular disease and diabetes as well as treatment therapy is presented for clinical consideration.
Surgery for Severe Obesity
- MedicineLifestyle Medicine
This state-of-the-art review focuses on the research and resultant recommendations regarding lifestyle management for patients who have undergone bariatric surgery.
Bariatric surgery as a treatment option in patients with type 2 diabetes mellitus.
- MedicineWorld journal of diabetes
The elucidation of the mechanisms underpinning the resolution of T2DM following bariatric surgery might result in the development of novel, more effective pharmacotherapies for this common disease.
Bariatric surgery: traversing the CROSSROADS into mainstream diabetes care
The CROSSROADS study was very successful in achieving weight loss and reducing markers of metabolic dysfunction, including HbA1c and fasting insulin concentrations in both arms, however, in keeping with previous studies on the effect of intensive lifestyle interventions on metabolic control in diabetes, and on weight loss, the initial improvements were not sustainable without the addition of surgery.
Gastric Bypass for Type 2 Diabetes Mellitus on BMI < 35
Bariatric surgery can cause resolution of the clinical manifestations of type 2 diabetes, as well as improvement, and metabolic surgery is the only diabetes treatment proven to result in long-term remission in 23–60% of patients depending upon preoperative duration of diabetes and disease severity.
SHOWING 1-10 OF 136 REFERENCES
IDF's view of bariatric surgery in type 2 diabetes
- MedicineThe Lancet
Bariatric surgery: an IDF statement for obese Type 2 diabetes.
- MedicineSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Bariatric Surgery on Type 2 Diabetes Mellitus Patients in Japan
Promoting weight loss without rebound is a major issue in treatment, especially in severely obese patients, and there has been an increase in patients with a BMI>35 undergoing bariatric surgery.
Bariatric surgery: unstressing or boosting the β‐cell?
- MedicineDiabetes, obesity & metabolism
Interestingly, a net improvement up to resolution of type 2 diabetes has been consistently reported few days after RYGB and BPD, and the mechanism allowing diabetes resolution after surgical intestinal manipulation is extremely interesting but only partially understood.
Narrative Review: Effect of Bariatric Surgery on Type 2 Diabetes Mellitus
- MedicineAnnals of Internal Medicine
Glycemic control in diabetic patients improves markedly within days of bariatric surgery, which suggests that the procedures alter the hormones that control insulin secretion, including ghrelin and peptide YY (PYY).
Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial.
People randomized to surgical therapy were more likely to achieve remission of type 2 diabetes through greater weight loss, and these results need to be confirmed in a larger, more diverse population and have long-term efficacy assessed.
Endocrine mechanisms mediating remission of diabetes after gastric bypass surgery
- MedicineInternational Journal of Obesity
Weight-independent antidiabetic actions of RYGB are apparent because of the very rapid resolution of T2DM, the greater improvement of glucose homeostasis after RY GB than after an equivalent weight loss from other means, and the occasional development of very late-onset, pancreatic β-cell hyperfunction.
Clinical Improvement After Duodenojejunal Bypass for Nonobese Type 2 Diabetes Despite Minimal Improvement in Glycemic Homeostasis
- MedicineWorld Journal of Surgery
Clinical improvement was obvious in all of the seven patients undergoing laparoscopic duodenojejunal bypass, but LDJB may not be effective at inducing remission of T2DM and the MS in certain patients undergoing this operation.
Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis.
- MedicineThe American journal of medicine
Effects of bariatric surgery on mortality in Swedish obese subjects.
- MedicineThe New England journal of medicine
Bariatric surgery for severe obesity is associated with long-term weight loss and decreased overall mortality.