Bariatric surgery for diabetes management

  title={Bariatric surgery for diabetes management},
  author={Katherine J Frachetti and Allison B Goldfine},
  journal={Current Opinion in Endocrinology, Diabetes and Obesity},
Purpose of reviewTo review the role of bariatric surgery in the treatment of patients with type 2 diabetes. Recent findingsMultiple studies demonstrate that bariatric surgical approaches to obesity lead to substantial and sustained weight loss. Patients with diabetes have remission of hyperglycemia or require reduced medications. Surgical intervention for patients with more recent diabetes onset may have higher rates of resolution than patients with longer duration disease. In addition… 

Cardiovascular benefits of bariatric surgery in morbidly obese patients

In morbidly obese patients bariatric surgery is safe and appears to reduce cardiovascular morbidity and mortality, and Laparoscopic Roux‐en‐Y gastric bypass (LRYGB) appears to be more effective than laparoscopic adjustable gastric banding (LAGB) in terms of weight loss and resolution of comorbidities.

Metabolic Laparoscopic Gastric Bypass for Obese Patients with Type 2 Diabetes

Gastric bypass in obese patients is associated with a high remission rate of diabetes and improvement of the metabolic control, and results suggest that this type of surgery might be particularly indicated for obese diabetic patients with good pancreatic reserve.

Techniques, assessment, and effectiveness of bariatric surgery in combating obesity

The techniques of the currently used surgical procedures and the clinical effectiveness of bariatric surgery are described and the possible complications and mortality rates after bariatric operations are discussed.

Preoperatively determinable factors predictive of diabetes mellitus remission following Roux-en-Y gastric bypass: a review of the literature

This paper summarises the existing literature on bariatric surgery and identifies which patients and which procedures are most likely to result in these desired benefits.

Bariatric surgery and the gut hormone response.

  • Susan ThomasP. Schauer
  • Medicine
    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
  • 2010
Bariatric surgery is reported to be the most effective method for achieving major, long-term weight loss, with weight loss ranges of 35%-40% lasting as long as 15 years, and the resultant metabolic changes have been linked to alterations in the gut hormones.

Assessment of Different Bariatric Surgeries in the Treatment of Obesity and Insulin Resistance in Mice

DIO mice had increased insulin promoter activity, suggesting overactivation of pancreatic beta cells, which was regulated by the mRYGB procedure, and the GI bypass procedure showed more severe symptoms of malnutrition following bariatric surgery.

Multiple Beneficial Effects of Laparoscopic Sleeve Gastrectomy for Patients with Obesity, Type 2 Diabetes Mellitus, and Restrictive Ventilatory Dysfunction

LSG not only controls the body weight and T2DM; it may also relieve pulmonary ventilation dysfunction in patients with obesity, type 2 diabetes mellitus, and RVD.

Roux-en-Y gastric bypass for morbid obesity: what are the preoperative predictors of weight loss?

Results however are variable and in order to optimise resource allocation and avoid exposing patients unlikely to benefit from surgery to its inherent risks, much research has been done to try to identify those patients most likely to obtain a good result.



Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial.

People randomized to surgical therapy were more likely to achieve remission of type 2 diabetes through greater weight loss, and these results need to be confirmed in a larger, more diverse population and have long-term efficacy assessed.

Effects of bariatric surgery on mortality in Swedish obese subjects.

Bariatric surgery for severe obesity is associated with long-term weight loss and decreased overall mortality.

Gastrointestinal Surgery for Severe Obesity.

A consensus panel recommended that patients seeking therapy for severe obesity for the first time should be considered for treatment in a nonsurgical program with integrated components of a dietary regimen, appropriate exercise, and behavioral modification and support.

Trends in bariatric surgical procedures.

Findings suggest that use of bariatric surgical procedures increased substantially from 1998 to 2003, while rates of in-hospital complications were stable and length of stay decreased.

Is Type 2 Diabetes an Operable Intestinal Disease?

Type 2 diabetes, which accounts for 90–95% of all cases of diabetes, is a growing epidemic that places a severe burden on health care systems, especially in developing countries. Because of both the

Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus.

LRYGBP resulted in significant weight loss (60% percent of excess body weight loss) and resolution of type 2 diabetes mellitus resolution after surgery, suggesting that early surgical intervention is warranted to increase the likelihood of rendering patients euglycemic.

NIH conference. Gastrointestinal surgery for severe obesity. Consensus Development Conference Panel.

  • Medicine
    Annals of internal medicine
  • 1991
The National Institutes of Health Consensus Development Panel recommended that patients seeking therapy for severe obesity for the first time should be considered for treatment in a nonsurgical program that integrates a dietary regimen, appropriate exercise, behavior modification, and psychological support.

Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients.

Concerns are raised about the characteristics of the matched-control subjects and the methods used for matching that generate concern for the possibility of uncontrolled confounding either by comorbidity or by socioeconomic status.

Current status of medical and surgical therapy for obesity.

Surgical therapy is the most effective modality in terms of extent and duration of weight reduction in selected patients with acceptable operative risks and the most widely performed surgical procedure, Roux-en-Y gastric bypass, achieves permanent and significant weight loss in more than 90% of patients.