Barbiturate treatment and membrane stability of subcellular organelles.

Abstract

The experimentally well established protective effect of barbiturate anaesthesia in cerebral ischaemia and increased intracranial pressure (ICP) has been assumed to be primarily a consequence of the reduction in cerebral metabolic rate. We present the results of studies of the influence of pentobarbitone on the stability of lysosomal membranes in the grey… (More)

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