Barbiturate tolerance: effects on GABA-operated chloride channel function
@article{Allan1992BarbiturateTE, title={Barbiturate tolerance: effects on GABA-operated chloride channel function}, author={Andrea M. Allan and Xiaoying Zhang and Lisa D. Baier}, journal={Brain Research}, year={1992}, volume={588}, pages={255-260} }
29 Citations
Region-specific changes of GABAA receptors by tolerance to and dependence upon pentobarbital.
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γ-Aminobutyric acidA receptor regulation: heterologous uncoupling of modulatory site interactions induced by chronic steroid, barbiturate, benzodiazepine, or GABA treatment in culture
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Chronic pentobarbital administration alters γ‐aminobutyric acidA receptor α6‐subunit mRNA levels and diazepam‐insensitive [3H]Ro15‐4513 binding
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- 1996
Data suggest that chronic pentobarbital treatment induced expression of α6‐subunit mRNA, a major component of the diazepam‐insensitive [3H]Ro15‐4513 binding site, which implied de novo synthesis of the receptor subunit protein.
Pressure-sensitive and -insensitive coupling in γ-aminobutyric acida receptors
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Abstract. Rationale: Previous behavioral and biochemical studies suggest that allosteric coupling processes initiated by benzodiazepines, barbiturates and neuroactive steroids can be sub-categorized…
Ethanol increases GABAA responses in cells stably transfected with receptor subunits.
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Analysis of data obtained from individual cells expressing alpha 1 beta 1-gamma 2L subunits showed considerable variability in sensitivity to ethanol, particularly with concentrations of 30 and 100 mM, suggesting the existence of ethanol-sensitive and -resistant receptors that may differ in subunit composition.
Benzodiazepine agonist and inverse agonist coupling in GABAA receptors antagonized by increased atmospheric pressure.
- Biology, ChemistryEuropean journal of pharmacology
- 2003
Behavioral sensitization to ethanol is modulated by environmental conditions, but is not associated with cross-sensitization to allopregnanolone or pentobarbital in DBA/2J mice
- Biology, PsychologyNeuroscience
- 2005
Discriminative stimulus effects of ethanol: neuropharmacological characterization.
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- 1999
Pharmacology of barbiturate tolerance/dependence: GABAA receptors and molecular aspects.
- BiologyLife sciences
- 1996
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