Banff Initiative for Quality Assurance in Transplantation (BIFQUIT): reproducibility of polyomavirus immunohistochemistry in kidney allografts.

@article{Adam2014BanffIF,
  title={Banff Initiative for Quality Assurance in Transplantation (BIFQUIT): reproducibility of polyomavirus immunohistochemistry in kidney allografts.},
  author={B A Adam and Parmjeet A Randhawa and Sharon Wing Wai Chan and Gang Zeng and Heinz M Regele and Yael B. Kushner and Robert B. Colvin and J. O. Reeve and Michael 4 Mengel},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2014},
  volume={14 9},
  pages={2137-47}
}
Immunohistochemistry (IHC) is the gold standard for diagnosing (positive vs. negative) polyomavirus BK (BKV) nephropathy and has the potential for disease staging based on staining intensity and quantification of infected cells. This multicenter trial evaluated the reproducibility of BKV IHC among 81 pathologists at 60 institutions. Participants stained tissue microarray slides and scored them for staining intensity and percentage of positive nuclei. Staining protocol details and evaluation… CONTINUE READING
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