Banff 07 Classification of Renal Allograft Pathology: Updates and Future Directions

@article{Solez2008Banff0C,
  title={Banff 07 Classification of Renal Allograft Pathology: Updates and Future Directions},
  author={Kim Solez and Robert B. Colvin and Lorraine C. Racusen and Mark Haas and Banu Sis and Michael Mengel and Phillip F Halloran and William M Baldwin and Giovanni Banfi and A. Bernard Collins and Fernando Cosio and D. S. R. David and Cinthia B. Drachenberg and Gunilla Einecke and Agnes B. Fogo and Ian W Gibson and Denis Glotz and S S Iskandar and Edward S. Kraus and Evelyne Lerut and R. B. Mannon and Michael J. Mihatsch and Brian J Nankivell and Volker Nickeleit and John C Papadimitriou and Parmjeet S. Randhawa and Heinz Regele and Karine Renaudin and Ian S. D. Roberts and Daniel Ser{\'o}n and R N Smith and Maria Valente},
  journal={American Journal of Transplantation},
  year={2008},
  volume={8}
}
The 9th Banff Conference on Allograft Pathology was held in La Coruna, Spain on June 23-29, 2007. [] Key Result Major updates from the 2007 Banff Conference were: inclusion of peritubular capillaritis grading, C4d scoring, interpretation of C4d deposition without morphological evidence of active rejection, application of the Banff criteria to zero-time and protocol biopsies and introduction of a new scoring for total interstitial inflammation (ti-score).
The Banff Conferences on renal allograft pathology – the latest 2013 report
TLDR
The latest Banff 2013 report is significant for the inclusion of a C4d-negative category under humoral rejection, together with the realisation that endarteritis may be antibody mediated, this latest report will greatly impact how pathologists interpret the allograft biopsy.
The Banff classification revisited.
TLDR
Despite the successes of the working classifications and ongoing collaborative efforts, there are limitations in this and other pathological classifications, related to potential for sampling error, issues of reproducibility when implemented globally, and lack of formal incorporation of morphometry and molecular and genomics approaches.
A 2018 Reference Guide to the Banff Classification of Renal Allograft Pathology
TLDR
This review shall provide a complete and simple illustrated reference guide of the Banff Classification of Kidney Allograft Pathology based on all publications including the 2017 update, intended as a concise desktop reference for pathologists and clinicians.
The art of classifying renal allograft pathology
  • J. Weening
  • Biology
    Nature Clinical Practice Nephrology
  • 2008
TLDR
The report advocates the application of the Banff schema to zero-time and protocol biopsies, and several working groups have been set up to investigate the importance of new research data (including genomics and proteomics) for practical use.
Cell mediated rejection revisited: Past, current, and future directions
  • S. Hara
  • Medicine, Biology
    Nephrology
  • 2018
TLDR
An overview of recent ideas on interstitial inflammation and vascular lesions based on emerging concepts of T‐cell‐mediated rejection are provided.
Impact of the Banff 2013 classification on the diagnosis of suspicious versus conclusive late antibody-mediated rejection in allografts without acute dysfunction.
TLDR
The Banff 2013 classification helps in making a diagnosis of late ABMR, identifying cases, decreasing the percentage of suspected ABMR and making more conclusive diagnoses.
Diagnosis of renal transplant rejection: Banff classification and beyond
  • H. Jeong
  • Medicine
    Kidney research and clinical practice
  • 2020
TLDR
In this review, morphologic features of renal transplant rejections as well as major revisions and pitfalls of the Banff classification system are discussed, and future perspectives are provided.
Immunohistochemical Scoring of C4d in Egyptian Patients with Chronic Renal Allograft Dysfunction
TLDR
A retrospective study for cases with biopsy proven chronic renal allograft damage diagnosed at nephropathology units comparing the variability between C4d scores in correlation with the available clinical data and histopathological parameters of chronicity.
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References

SHOWING 1-10 OF 44 REFERENCES
The Banff 97 working classification of renal allograft pathology.
TLDR
Major changes include the following: rejection with vasculitis is separated from tubulointerstitial rejection; severe rejection requires transmural changes in arteries; "borderline" rejection can only be interpreted in a clinical context; antibody-mediated rejection is further defined, and lesion scoring focuses on most severely involved structures.
Banff '05 Meeting Report: Differential Diagnosis of Chronic Allograft Injury and Elimination of Chronic Allograft Nephropathy (‘CAN’)
  • K. Solez, R. Colvin, J. Weening
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2007
TLDR
The 8th Banff Conference on Allograft Pathology was held in Edmonton, Canada, 15–21 July 2005, and major outcomes included the elimination of the non‐specific term ‘chronic allograft nephropathy’ (CAN) and the recognition of the entity of chronic antibody‐mediated rejection.
The fate of C4d positive kidney allografts lacking histological signs of acute rejection.
TLDR
C4d positivity in kidney transplants lacking histological evidence of acute rejection is not associated with rapid functional graft deterioration, even in untreated cases, and anti-rejection therapy results in the improvement of kidney function.
Incidence of C4d Stain in Protocol Biopsies from Renal Allografts: Results from a Multicenter Trial
  • M. Mengel, J. Bogers, H. Haller
  • Medicine, Biology
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2005
TLDR
Diffuse and focal C4d stain correlated with morphology of humoral rejection in protocol as well as in indication biopsies, showing a significantly lower incidence of C4D deposition than indicationBiopsies.
Protocol Biopsies in Renal Transplantation: Insights into Patient Management and Pathogenesis
  • M. Mengel, J. Chapman, R. Colvin
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2007
TLDR
A 1‐day symposium on the application of protocol biopsies in renal transplantation was held in Boston, 21 July 2006 and the consensus was that protocolBiopsies, in experienced hands, are a safe and valuable means of detecting subclinical disease that can benefit from modification of therapy.
Antibody‐Mediated Rejection Criteria – an Addition to the Banff ′97 Classification of Renal Allograft Rejection
  • L. Racusen, R. Colvin, K. Trpkov
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2003
TLDR
This article presents international consensus criteria for and classification of AbAR developed based on discussions held at the Sixth Banff Conference on Allograft Pathology in 2001, to be revisited as additional data accumulate in this important area of renal transplantation.
Subclinical Rejection Associated with Chronic Allograft Nephropathy in Protocol Biopsies as a Risk Factor for Late Graft Loss
  • F. Moreso, M. Ibernon, D. Serón
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2006
TLDR
In protocol biopsies, the detrimental effect of interstitial fibrosis/tubular atrophy on long‐term graft survival is modulated by SCR, and Cox regression analysis showed that SCR with CAN and hepatitis C virus were independent predictors of graft survival.
Protocol biopsies in renal transplantation: prognostic value of structural monitoring.
TLDR
Quantification of renal damage is associated with graft survival suggesting that quantitative parameters might improve the predictive value of protocol biopsies.
Histologic Findings of Antibody‐Mediated Rejection in ABO Blood‐Group‐Incompatible Living‐Donor Kidney Transplantation
  • M. Fidler, J. Gloor, M. Stegall
  • Medicine, Biology
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2004
TLDR
AMR is characterized by glomerular thrombi, mesangiolysis, peritubular capillary neutrophil infiltration interstitial hemorrhage, necrosis, and C4d deposition, and may appear prior to graft dysfunction.
Microarray Analysis of Rejection in Human Kidney Transplants Using Pathogenesis‐Based Transcript Sets
  • T. Mueller, G. Einecke, P. Halloran
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2007
TLDR
Many transcriptome changes previously described in rejection are features of a large‐scale disturbance characteristic of rejection but occurring at lower levels in many forms of injury, indicating that transcriptome disturbances in renal transplants have a stereotyped internal structure.
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