Banded chromosome analysis in patients with treatment-associated acute nonlymphocytic leukemia.

@article{Arthur1984BandedCA,
  title={Banded chromosome analysis in patients with treatment-associated acute nonlymphocytic leukemia.},
  author={Diane C. Arthur and Clara D. Bloomfield},
  journal={Cancer genetics and cytogenetics},
  year={1984},
  volume={12 3},
  pages={189-99}
}
We have analyzed G-banded metaphase chromosomes from 20 patients with treatment-associated acute nonlymphocytic leukemia (t-ANLL). Nine patients were previously treated for hematologic malignancies and 11 for solid tumors. The interval from initial therapy to t-ANLL ranged from 35 to 182 mo (median 75.5 mo). Medial age at diagnosis of t-ANLL was 58.5 years. Clonal chromosome abnormalities were found in 19 patients (95%). Loss or partial deletion of the long arm of chromosomes #5 and/or #7 were… CONTINUE READING

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