Band 3 tyr-phosphorylation in normal and glucose-6-phospate dehydrogenase-deficient human erythrocytes.

@article{Bordin2005Band3T,
  title={Band 3 tyr-phosphorylation in normal and glucose-6-phospate dehydrogenase-deficient human erythrocytes.},
  author={Luciana Bordin and Francesco Zen and Florina Ion-Popa and Micaela Barbetta and Bruno Baggio and Giulio Clari},
  journal={Molecular membrane biology},
  year={2005},
  volume={22 5},
  pages={411-20}
}
Haemolysis is usually episodic in glucose-6-phosphate dehydrogenase (G6PD) deficiency, often triggered by a period of oxidative stress. In the present work, we investigate a possible biochemical mechanism underlying the enhanced susceptibility of G6PD deficient red blood cells (RBC) to oxidative stress. We analysed eight male subjects with Mediterranean glucose-6P-dehydrogenase deficiency (G6PDd), class II, for their ability in phosphorylating erythrocyte membrane band 3 following oxidative and… CONTINUE READING

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