Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis.

  title={Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis.},
  author={Carolin Lackner and Margit Gogg-Kamerer and Kurt Zatloukal and Conny Stumptner and Elizabeth M. Brunt and Helmut Denk},
  journal={Journal of hepatology},
  volume={48 5},
BACKGROUND/AIMS Hepatocyte "ballooning" is an often used but ill defined term in liver pathology to designate a special form of liver cell degeneration associated with cell swelling and enlargement found particularly in steatohepatitis. Alterations of the intermediate filament cytoskeleton of the hepatocyte may contribute to the pathogenesis of this microscopic change. Ballooning degeneration is considered a hallmark of steatohepatitis, but enlarged hepatocytes may also be observed in a variety… CONTINUE READING


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