Balloon angioplasty induces heat shock protein 70 in human blood vessels.

@article{Kirby1999BalloonAI,
  title={Balloon angioplasty induces heat shock protein 70 in human blood vessels.},
  author={Lem Kirby and J Sheppard Mondy and Colleen Marie Brophy},
  journal={Annals of vascular surgery},
  year={1999},
  volume={13 5},
  pages={475-9}
}
Balloon angioplasty produces a mechanically induced injury to the blood vessel wall. Heat shock protein 70 (HSP70) is a molecular chaperone whose expression can be induced by chemical or thermal stress. Thus, we hypothesized that the mechanical injury associated with balloon angioplasty would lead to increases in the expression of HSP70 in vascular smooth muscle. Segments of popliteal and trifurcation vessels from above-the-knee amputations were subject to transluminal balloon angioplasty… CONTINUE READING