Balancing the immune system: Th1 and Th2.

  title={Balancing the immune system: Th1 and Th2.},
  author={Willem van Eden and Ruurd van der Zee and Peter J.S. van Kooten and Suzanne E. Berlo and Pieter M. Cobelens and Annemieke Kavelaars and Cobi J Heijnen and Berent A Prakken and Sarah TA Roord and Salvatore Albani},
  journal={Annals of the rheumatic diseases},
  volume={61 Suppl 2},
CD4+ T cells are subdivided into Th1 and Th2 cells. Their relative presence or activation is thought to have a regulatory effect on immune behaviour. Until recently, the relative suppression of Th1 cells by the relative increase of Th2 activities, was thought to be a main mechanism of keeping or restoring the balance in a diseased immune system. Nowadays, however, a specialised subset of regulatory T cells is held to be responsible for the main effects of securing a balanced immune system. It… CONTINUE READING