Balancing and directional selection at exon-2 of the MHC DQB1 locus among populations of odontocete cetaceans.

@article{Vassilakos2009BalancingAD,
  title={Balancing and directional selection at exon-2 of the MHC DQB1 locus among populations of odontocete cetaceans.},
  author={Demetrios Vassilakos and Ada Natoli and Marilyn Dahlheim and A Rus Hoelzel},
  journal={Molecular biology and evolution},
  year={2009},
  volume={26 3},
  pages={681-9}
}
The diversity of exon-2 (peptide-binding region) of the DQB1 locus (Class II, major histocompatibility complex, MHC) was investigated on an extended sample of populations of three focal cetacean species (two sibling delphinid species and another in the same family). We tested the hypothesis that dolphin populations with a worldwide distribution across different habitats and geographic regions will be under differential selective pressure by comparing DQB1 variation with variation at neutral… CONTINUE READING

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