Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation.

@article{Aksu2012BalancedVU,
  title={Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation.},
  author={Uğur Aksu and Rick Bezemer and Berna Yavuz and Asli Kandil and Cihan Demirci and Can Ince},
  journal={Resuscitation},
  year={2012},
  volume={83 6},
  pages={
          767-73
        }
}
BACKGROUND The aim of the present study was to test the hypothesis that balanced crystalloid resuscitation would be better for the kidney than unbalanced crystalloid resuscitation in a rat hemorrhagic shock model. METHODS Male Wistar rats were randomly assigned to four groups (n=6/group): (1) time control; (2) hemorrhagic shock control; (3) hemorrhagic shock followed by unbalanced crystalloid resuscitation (0.9% NaCl); and (4) hemorrhagic shock followed by acetate and gluconate-balanced… CONTINUE READING

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